| Eastbound | Westbound | Northbound | Southbound |
| Eastbound Trains | |||
| Departure Time | Train Number | Origin-Destination | Through Service to: |
|---|---|---|---|
| The Erie Limited | |||
| 7:34 AM | Erie No.2 | Chicago to New York | New York via Chambers Street Ferry |
| The Atlantic Express | |||
| 11:27 AM | Erie No.8 | Chicago to New York | New York via Chambers Street Ferry |
| The Philadelphia Express (Erie Section) | |||
| 7:18 PM | PRR No.580 | Erie to Philadelphia | Merges with Pittsburgh section at Harrisburg |
| The Lake Cities | |||
| 9:17 PM | Erie No.6 | Chicago to New York | New York via Chambers Street Ferry |
| Northbound Trains ↑ | |||
| Departure Time | Train Number | Origin-Destination | Through Service to: |
|---|---|---|---|
| 4:59 AM | PRR No.914 | Pittsburgh to Buffalo | |
| The Northern Express | |||
| 10:14 AM | PRR No.575 | Harrisburg to Erie | |
| Southbound Trains ↑ | |||
| Departure Time | Train Number | Origin-Destination | Through Service to: |
|---|---|---|---|
| 1:30 AM | PRR No.911 | Buffalo to Pittsburgh | |
| 8:20 AM | PRR No.981 | Corry to Oil City | |
| The Southern Express (PA Section) | |||
| 7:02 PM | PRR No.0 | Erie to Harrisburg | |
| Westbound Trains ↑ | |||
| Departure Time | Train Number | Origin-Destination | Through Service to: |
|---|---|---|---|
| The Lake Cities | |||
| 7:19 AM | Erie No.5 | New York to Chicago | At Youngstown, Lake Cities separates to Cleveland1 |
| The Pacific Express | |||
| 1:06 PM | Erie No.7 | New York to Chicago | |
| The Erie Limited | |||
| 8:53 PM | Erie No.1 | New York to Chicago | |
| 9:25 PM | PRR No.973 | Emporium to Erie | |