| Eastbound | Westbound | Northbound | Southbound |
| Eastbound Trains | |||
| Departure Time | Train Number | Origin-Destination | Through Service to: |
|---|---|---|---|
| The Philadelphia Express (Erie Section) | |||
| 1:38 AM | PRR No.580 | Erie to Philadelphia | Merges with Pittsburgh section at Harrisburg |
| 2:25 AM | PRR No.856 | Williamsport to Harrisburg | Philadelphia and New York via No 70 |
| The Susquehannock | |||
| 6:30 AM | PRR No.632 | Williamsport to Philadelphia | New York via No 210 |
| 2:48 PM | PRR No.510 | Altoona to Scranton | |
| The Washington and Buffalo Express | |||
| 2:48 PM | PRR No.570 | Buffalo to Philadelphia | New York via No 268, To Washington via PB&W |
| 3:30 PM | Reading No.12 | Newberry to Port Clinton | Philadelphia via No 12 |
| 10:07 PM | Reading No.14 | Newberry to Philadelphia | |
| Northbound Trains ↑ | |||
| Departure Time | Train Number | Origin-Destination | Through Service to: |
|---|---|---|---|
| The Dominion Express | |||
| 1:52 AM | PRR No.575 | Harrisburg to Buffalo | |
| 2:35 AM | NCEN No.851 | Williamsport to Canandiagua | To Rochester, Buffalo, Niagara Falls via NYC No |
| The Northern Express | |||
| 2:48 AM | PRR No.575 | Harrisburg to Erie | |
| 5:55 AM | PRR No.577 | Harrisburg to Emporium | |
| 2:09 PM | PRR No.971 | Harrisburg to Buffalo | Emporium PA to Erie PA via No 973 |
| The Buffalo Day Express | |||
| 2:09 PM | PRR No.571 | Harrisburg to Buffalo | |
| 2:55 PM | NCEN No.857 | Williamsport to Canandiagua | To Rochester, Buffalo via NYC No |
| Southbound Trains ↑ | |||
| Departure Time | Train Number | Origin-Destination | Through Service to: |
|---|---|---|---|
| The Southern Express (PA Section) | |||
| 2:16 AM | PRR No.0 | Erie to Harrisburg | |
| The Dominion Express | |||
| 2:56 AM | PRR No.574 | Buffalo to Harrisburg | Washington via PB&W, To Philadelphia via No 604 |
| 11:10 AM | PRR No.500 | Williamsport to New York | Washington via PB&W |
| The Washington Express | |||
| 4:37 PM | PRR No.570 | Buffalo to Harrisburg | |
| 7:50 PM | PRR No.578 | Emporium to Harrisburg | Philadelphia via No 18, To New York via 52 |
| Westbound Trains ↑ | |||
| Departure Time | Train Number | Origin-Destination | Through Service to: |
|---|---|---|---|
| 7:53 AM | Reading No.11 | Philadelphia to Newberry | |
| 5:19 PM | Reading No.5 | Philadelphia to Newberry | Port Clinton to Pottsville via No 5 |
| 6:30 PM | PRR No.501 | Harrisburg to Altoona | Pittsburgh via PRR No 71 |